114-2-醫學三-23腸胃內科
Esophageal motility disorders是導因於esophageal neuromuscular dysfunction,關於不同的esophageal motility disorders,下列敘述何者正確?
Aachalasia病因是loss of ganglion cells within the esophageal myenteric plexus,臨床罕見,發生率約為1/100,000,好發於60~80歲年邁族群
Beosinophilic esophagitis的臨床表徵是episode of dysphagia and chest pain,在X光攝影下可能呈現corkscrew esophagus、rosary bead esophagus、pseudodiverticula
Cdiffuse esophageal spasm的發生率逐年增加,其食道切片檢查可發現squamous epithelial eosinophil-predominant inflammation,其對口服類固醇的效果良好
Dgastroesophageal reflux disease為相當盛行的文明病,其致病機轉包括transient lower esophageal sphincter(LES)relaxation、LES hypotension、anatomical distortion
核心考點
這題要辨別四種食道動力疾病(achalasia、eosinophilic esophagitis、diffuse esophageal spasm、GERD)的核心特徵,考的是有沒有把各疾病的臨床、影像、病理、治療搞混。